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KMID : 1004820130140020128
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Journal of Biomedical Research
2013 Volume.14 No. 2 p.128 ~ p.131
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A case of metastatic cholangiocarcinoma in a ferret
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Lee Ho-Suk
Kang Kyung-Ku
Min Chang-Woo
Kim Ah-Young
Lee Eun-Mi
Lee Eun-Joo
Lee Myeong-Mi
Kim Sang-Hyeob
Sung Soo-Eun
Jeong Kyu-Shik
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Abstract
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Cholangiocarcinoma is a relatively rare neoplasm in animals and humans. A four-year-old, neutered male ferret presented with depression, anorexia, cachexia, diarrhea, and icterus. Necropsy findings included ascites, multiple white nodules on the surface of the liver, stomach, and duodenum, gross enlargement of the bile duct and right atrium, hemorrhage of the gastric and duodenal mucosa, and icterus of the mesenteric fat. Infiltrative well-differentiated neoplastic biliary epithelial cells forming ducts and acini with a prominent collagenous stroma were observed on microscopic examination of neoplastic lesions within the liver, mesentery, and the serosa of the stomach and duodenum. This is a report on a rare case of obstructive jaundice due to cholangiocarcinoma in a ferret.
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KEYWORD
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cholangiocarcinoma, ferret, metastasis, obstructive jaundice
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